Although G6PD deficiency, which can cause problems in red blood cells upon certain triggers, is the most common human enzyme defect, affecting over 400 million people, including over 1 in 10 Black Glutathione Synthesis and Turnover in the Human Erythrocyte Journal of Biological Chemistry Rasburicase Induced Hemolytic Anemia Secondary to Undiagnosed G6PD Deficiency Published in Journal of Brown Hospital Medicine The Electron Transport Chain and Pentose Phosphate Pathway biochemistry